Has your continuous improvement kept up with your business? It is a new era for manufacturing, and a new era for continuous improvement (CI) is available too. This eBook gives you ideas for how to update your CI with digital support and new approaches that ensure you build on your CI successes. We interviewed manufacturers,…
- Executive Overview
- New Era in Manufacturing
- The Problem-Solving Story
- Five New-Era CI Needs
- New Era in Manufacturing
- Expected and Engaging
- Distributed and Elevated
- Diverse Yet Harmonized
- Learning-focused and Digital
- Enabling CI Sequels
- Recommendations
- Acknowledgments
- About the Author
Executive Overview
There’s a new Era in Manufacturing; it is time for a new era of continuous improvement (CI). This is a time of digital approaches delivering an array of new capabilities and insights that can move the business beyond unpleasant trade-offs. In this new era, CI gets enterprise-wide standardization and support and keeps the enthusiasm of local teams and employees. It delivers both local breakthroughs and views that support executives in understanding progress and prioritizing resources for the following CI projects in ways that make sense to everyone. Appropriate digitalization enables CI teams to get rapid and reliable access to all the data they need from a wide variety of sources. Beyond that, it supports them in gaining rich insights from the data with far less effort than ever before. Goals and results are translated into a shared, visceral unit of improvement that matters to shop floor operators, supervisors, managers, and executives: time. By feeding shared understanding, this digitally-supported CI will more likely generate enthusiasm and benefits even as the business shifts and changes.
The Problem-Solving Story
Path to Success
The Toyota Way points to a complete approach to solving problems – or making systemic improvements. The elements are:
- Developing a thorough understanding of the current situation and define the problem
- Complete a thorough root cause analysis
- Thoroughly consider alternative solutions while building consensus
- Plan-Do-Check-Act (PDCA)
- Plan: Develop an action plan
- Do: Implement solutions rapidly
- Check: Verify the result
- Act: Make necessary adjustments to solutions and action plan and determine future steps
- Reflect and learn from the process
Enabling CI Sequels
Each step of the CI story can benefit from having digital data available.
- Understanding: The complete set of correct data easily available and analyzed leads to a deeper understanding of the current situation and an accurate definition of the problem.
- RCA: Completing a thorough root cause analysis, such as tree diagramming, is faster and more assured when data is accessible, trusted, and complete.
- Modeling alternative solutions: When all parties trust and can see the data and its provenance, modeling to evaluate alternatives can be a clear and effective way to build consensus.
- Plan-Do-Check-Act (PDCA):
- Plan: Developing and recording the action plan in an IT system enables all to see and contribute equally.
- Do: Implementing solutions can come sooner when generating the plan is faster and the means to monitor progress is in place. The digital system can also help keep everyone in sync with rapid action.
- Check: Evaluating is a data-based exercise, so having a coherent system designed to record progress and unintended consequences in an unbiased and automatic way can contribute to effective and efficient CI.
- Act: Everyone can also participate fully and trust when they can see the basis for making necessary adjustments to solutions and the action plan
- Reflect: A consistent digital system can also facilitate learning from the process. People agree on the data and can use the system to record what they learned and what logic they used to direct future projects.

Table of Contents
- Continuous IT Architectural Transition
- Impact on Software ROI and TCO
- Impact on People, Process, and Technology
- Changing the Status Quo
- Plan for the Future
- Acknowledgments
Introduction
The Evolution of Software Architectures Impacts ROI
Changing the Status Quo
The Status Quo is High TCO and Reduced ROI Software transition is challenging and expensive, simultaneously impacting people, process, and technology. This leads to companies holding on to systems beyond their useful life and waiting until they are forced to make a change. For example, our research shows that the median time of company’s last primary PLM system upgrade is about 3.3 years ago, and most companies have multiple solutions for legacy reasons.2 These older systems should have been changed, but manufacturers can’t face the disruption and don’t want to suffer the need to rip and replace applications. Technology architecture waves are one of the most common things to force companies to change these systems. Breaking the Rip-and-Replace Cycle Part of the challenge leading to the need to abandon older, comfortable systems is the way most systems are architected. The most common approach creates direct and indirect interdependencies between the software interface, logic, code, data model, and infrastructure. A less common approach, model-based programming, breaks this paradigm by separating business logic and data models from the underlying software architecture that delivers it. Our research shows that a model-based approach, now commonly known as low-code or no-code software, increases companies’ agility and their ability to digitally transform.3 Low-code also allows the software architecture, the service layer, to change underneath while retaining the investment in the application logic and data model. It makes the underlying IT infrastructure, how you operate the software, independent of the solution. This makes applications much easier to upgrade and breaks the need to rip-and-replace solutions to take advantage of a new technical architecture. It offers continuity of functionality, customizations, extensions, integrations, and reporting during upgrades, including architecture transition. There is still work to do to make the transition to a new architecture, but the vast majority of that work is in the inner workings of the system and accomplished by a smaller team within the IT department or the software provider. The rest is insulated from the technical disruption. Reducing the Impact A low-code approach, therefore, allows companies to transition to new architectures and adopt new technologies with far less impact on people, process, and technology. It allows companies to maintain the value of their existing solutions while decreasing cost, risk, and disruption during the transition. This allows companies to more rapidly transition to new architectures with higher ROI and decreased TCO. Beyond the transition, the resulting agility and lack of disruption allows manufacturers to continuously improve to increase the value they receive from software while protecting the investments they’ve already made in people, process, and technology.
Plan for the Future
Technology Waves are Here to Stay
Technology waves will continue and the value they offer will be compelling. Migrating to these new architectures, however, will reduce the value and increase the cost of applications during the transition. Most companies are facing the Cloud / SaaS transition in some or all of their applications, and arguably facing a simultaneous transition from corporate computing to a more mobile, work from anywhere, multi-device paradigm. Businesses must be strategic about how they make the transition.
Increase ROI and Decrease TCO with Low-Code
Now is the time to break the need to rip-and-replace applications to accommodate the cloud and future architecture transitions. Companies can learn from others who invested in low-code solutions and are able to retain their current investment in applications while migrating the underlying computing architecture. This approach maintains the high level of value companies receive from their solutions without taking a significant step back in capabilities. It also reduces the cost, risk, and disruption of the transition.
Adopting low-code solutions insulates companies from architecture waves and allows them to achieve an optimal application ROI and TCO. Companies transitioning to the cloud should make the change thoughtfully, adopting a system that protects them from the factors that limit benefits and drive high costs. At the same time, they should look for a solution that delivers the functional capabilities they need to optimize their business. Selecting a composable, low-code solution with an application library protects their investment because their existing applications ride on top of the technology waves during future transitions as the app library simultaneously offers new functional capabilities to adopt as valuable.
*This summary is an abbreviated version of the research and does not contain the full content. For the full research, please visit our sponsor Aras (registration required).
If you have difficulty obtaining a copy of the report, please contact us.
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[post_content] => We had a fascinating update briefing with Gridraster COO/Co-founder Dijam Panigrahi, highlighting the growing potential of XR and spatial computing. When we first spoke with them a couple of years ago, we were excited about their platform and what it offers their application provider partners. Namely, Gridraster provides the infrastructure they need to deliver solutions with remote rendering, precise 3D spatial mapping of virtual objects in mixed reality, and other enablers that unlock the power of the metaverse.
One of the reasons Julie Fraser and I like speaking with Gridraster is that they do quite a bit of work in the aerospace and defense industry. A&D helped pioneer #virtualreality and continues to push the maturity of what mixed reality can do. They have also been leading proponents of digital twins, where Gridraster can provide the granular data underpinning for the industrial metaverse. Of course, it’s hard to discuss XR right now without mentioning Apple. As Dijam told us, “With Apple coming in, the new word is spatial.” The introduction of the Apple Vision Pro created a lot of enthusiasm about the metaverse across industries and should contribute to new use cases and greater adoption.

However, technology is only one part of the equation; gaining real business value is another. Manufacturers are starting to gain more confidence in spatial computing and beginning to achieve real value. Gridraster is working with manufacturers that are applying XR across the product lifecycle, from engineering through support. Some of the critical use cases they’re working with customers and partners on include:
- Improving quality assurance by comparing expected geometry with scanned geometry, whether holographically with headsets or by leveraging other scanners, in near real-time
- Creating high-precision digital twins for existing assets, for example, creating a 3D reconstruction of a physical item without existing 3D designs to support simulation, operations, or training
- Supporting manufacturing by determining the 3D coordinates of a work piece in a robotic work environment to pass along to industrial robots
- Improving maintenance and inspections by scanning with a camera and stitching together multiple scans to create a 3D model to map out an entire interior space without a person physically entering the space
- Supporting maintenance and inspection technicians with active task guidance by overlaying digital instructions over the physical environment
Dijam explained that one of their most compelling capabilities to support these use cases is their ability to capture geometry with millimeter-level accuracy. With this, they can create very precise renderings or compare “as expected” digital models with the scanned truth with high precision and identify discrepancies with very high accuracy.
Our research shows that it may still take some time for XR and the industrial metaverse to become pervasive tools in the manufacturing industries, at least outside of larger companies and industries like automotive and A&D. Still, our discussions with GridRaster Inc. show that the value is available, and we believe the barriers will continue to drop. As devices become more capable, computing power grows, and platforms become more accessible, at least in some part due to the gaming industry, we expect further adoption. Thank you, Dijam Panigrahi to keep us in the “believers” camp for greater adoption – and value – from AI and XR. And thanks to John Sternal for coordinating the discussion.
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ComplianceQuest has expanded its product footprint with the ProductQuest (PLM) suite alongside the existing QualityQuest (QMS) and SafetyQuest (EHS) suites. In all, there are 28 products in these three suites. All these applications are integrated on the ComplianceQuest Digital Quality+ platform. If you know the company, you know the software is natively built on the Salesforce Business Cloud platform. ComplianceQuest partners with Salesforce effectively to take advantage of their Force Cloud platform, applications, and ecosystem opportunities.
Last year, new functionality releases included Digital SOPs, CQ.Forms, (both online and offline) PLM, and FMEAs and Control Plans (APQP) for its Design Quality solution, connections from regulations and standards to auditing, an Intake Wizard to quickly guide users to report a nonconformance, a Response Wizard that helps create all the required records needed in an audit finding, Change Control impact assessment, and Supplier Performance rating system. In the AI space, they added CQ.AI agents, enhanced Next Best Actions/tasks (NBA) to drive more than workflow but tasks/steps as well, embedded analytics with AI in non-conformance and complaints so separate reports are no longer necessary, Intelligent Analytics for better current and predictive visibility, and Quality Maturity Index (QMI) to assess quality across the entire organization and by location.
ComplianceQuest targets both Life Sciences and Manufacturing industries. They have also made progress in the government / public sector with a FedRAMP attestation. Their integrator and reseller partner network continues to expand as the company gains customers of all sizes. Sales are also growing in Europe and Asia Pacific English-speaking countries.
ComplianceQuest’s unified solution approach is increasingly attractive as companies seek to improve the success of digital transformation and roll out the same applications across their enterprise. With quality management (QMS), environmental health and safety (EHS), and now quality-focused product lifecycle management (PLM) all on a single platform, ComplianceQuest customers have a strong data flow for the quality digital thread. Those who use the Force.com platform for other purposes can avoid integration headaches even more broadly.
The platform has AI and other decision-making enablers built into it. ComplianceQuest emphasizes the data-driven approach, a break from the document-driven approach of many historical QMS products.
Thank you,Nikki Willett, for taking the time to update us. We look forward to a deeper dive into PLM for product quality and following ComplianceQuest’s continuing growth in the market.
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Table of Contents
- The Design-Build Project Approach
- Construction Delivery Models
- What is Design-Build?
- The Benefits of Using Design-Build
- Challenges and Risks of the DB Model
- The Role of Technology in Enabling Design-Build
- Recommendations and Next Steps
- Acknowledgments
Executive Summary
Real estate development is driven by the capitalistic pursuit of opportunity in the face of an imbalance of building supply compared with demand. It is an industry where the final product is most often unique. The business objective of delivering results at the lowest possible cost in light of defined quality objectives and time remains consistent across teams and cultures. Design-build (DB) is a delivery model that has gained significant appeal because of the opportunity to realize savings with the acceptance of slightly more risk but greater transparency with regard to cost. Teamwork and collaboration are at the core of DB, versus the typical disassociated approach of steering design and then seeking fixed-price bids from general contractors. DB inherently incentivizes all parties to identify ways to improve productivity and quality while offering a level of fairness and cost transparency. The cost data understood from prior DB projects contributes to greater awareness heading into new projects. Further, the early involvement of construction trade teams offers architects and designers ongoing feedback as they evolve the design with regard to product and productivity. This environment of collaboration serves to positively impact cost, schedule, and quality; reducing the risk of missing the mark with design and ensuring a tighter trade buy-out process during construction. This eBook takes an in-depth dive into Design-Build in relation to other design and construction delivery frameworks based on discussions with residential real estate development firms who have either adopted this approach or at least experimented with it. It reviews how workflows have evolved in time, the factors that drive a DB approach, and the benefits anticipated. It also highlights the increasing importance of technology adoption for communication across teams, design-build validation, and planning.Construction Delivery Models

Recommendations and Next Steps
Design-Build is Driving Change Real estate development projects are high-risk, intense endeavors. Inner-city projects begin with high-value land acquisitions and significant design and municipal fees. Lenders often require 50% pre-sales, and construction financing commitments are generally predicated on building permit releases. Considerable funds are at risk before construction ever sees the light of day. Team focus is first on the entitlement and underwriting process; then, with the re-zoning approvals, the design development begins. As architects and the discipline designers advance towards a development permit and then a building permit the opportunity for trade feedback presents itself regularly. Our research and experience found that design complexity continues to increase, leading to an industry shift to adopt a more integrated and collaborative design approach. Legal frameworks and the fragmented nature of the industry drive a conservative mindset more resistant to change than other industries; however, advances in technology toolsets, the cloud, and software platform approaches are causing practices and approaches to change. These industry catalysts are driving many teams to look to Design-Build to create a more cohesive and cost-effective experience of RE projects, delivering benefits such as schedule compressions, target-value design and delivery, and a fiscal balance reflecting finish quality. Technology Supports DB and Overall Construction Profitability The real wins are reducing cycle times related to project feasibility studies, design development, interfacing with municipal planners, construction cost estimating, third-party quantity surveyors, project managers, general contractors, and trade contractors. It’s about understanding what is permitted to build and creating greater value propositions with project proformas. Authoring tools that facilitate accurate geometry and visualization are critical aids for extended teams to access project data and support them in driving results. The future is about speedier data retrieval and more integrated systems. Access to accurate data will be quick as the design and construction delivery world moves into a 3D paradigm. Data drives the ability to make decisions. The recent advent of deep machine learning models and Artificial Intelligence (AI) also promises significant acceleration in access to data and generative AI will shorten cycle times. However, as much as software may drive the potential for productivity, the banking industry and the municipal bureaucracy structures must also adapt and improve access to and acceptance of data and graphical models. The choke points will soon be with user adoption and training. This cannot be overlooked. We believe design-build will continue to grow in the real estate development market. It creates deeper cohesion amongst project participants. And it hits the bull’s eye for driving cost-efficient projects. Developers that adopt more technology and continue with sound financial and contracting practices appear to be able to better leverage design-build contract arrangement to improve overall cost, speed, and quality. *This summary is an abbreviated version of the research and does not contain the full content. For the full research, please visit our sponsor Graphisoft (registration required). If you have difficulty obtaining a copy of the report, please contact us. [post_title] => Supporting Design-Build in Real Estate Development [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => design-build [to_ping] => [pinged] => [post_modified] => 2024-04-22 11:06:47 [post_modified_gmt] => 2024-04-22 15:06:47 [post_content_filtered] => [post_parent] => 0 [guid] => https://tech-clarity.com/?p=20111 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [5] => WP_Post Object ( [ID] => 20128 [post_author] => 2574 [post_date] => 2024-04-19 09:00:06 [post_date_gmt] => 2024-04-19 13:00:06 [post_content] =>






Table of Contents
- The Value of an Integrated Lab Environment
- The Five Dimensions of Lab Integration
- People
- Process
- Software
- Hardware
- Data
- Next Steps
- Acknowledgments
Introduction
Chemical Labs are Overdue for Digital Transformation Chemical labs are critical to every aspect of manufacturing, from R&D through scaleup to operations. While manufacturers have continuously improved product quality and manufacturing productivity through continuous improvement and digital transformation, the lab is often left out of these initiatives. That leaves lab managers with a patchwork of solutions and disjointed processes that burden scientists and technicians with non-value-added work. Poorly integrated lab environments take highly trained lab resources away from innovating and slow down product development, product launch, and product release. It's time to get the most out of the lab through continued digital transformation. We've identified five dimensions to measure and improve lab integration to optimize lab operations and enhance overall business performance. These dimensions include better integration between people, process, and technology in the lab, including integration of systems around a common data model. We'll look at each of the dimensions in detail and discuss how taking a platform approach helps achieve them.

Next Steps
Recognize the Opportunity Today's lab environment is ripe for improvement. Most chemical labs’ productivity hasn’t continuously improved on par with other operations in the manufacturing enterprise. There is still too much inefficiency, inability to find and reuse data, and patchworks of solutions. Lack of integration leads to inefficiency, delays, and a lack of agility in the status quo. It's time to digitally transform and integrate the lab across people, process, and technology using a platform approach to speed up the lab and resulting product development, launch, and release. Get Started Ultimately, companies should integrate from ideation to production in the plant, creating a data continuum or digital thread with effective data governance across the product lifecycle. Most companies should start small. It's essential that they understand their starting point by objectively evaluating their capabilities and identifying what must be improved. But, they shouldn’t expect to change everything at once and they don't have to reinvent the wheel; they can reuse existing methods and processes already developed. Further, they can extend these with simple, out-of-the-box methods. Plan for Success Lab managers have to look at increasing integration across people, process, and technology programmatically with an emphasis on data. It's critical to get management support for their effort and communicate the value in business terms. They must also make sure the lab is involved, sees the advantage for them, and feels empowered to make needed changes. It's important to recognize that this is a journey. Effectively updating people, process, and technology takes time. It's OK to start small but have a plan that leads to fully digital, integrated people, processes, and technology to drive speed and accuracy. But it's time to get started. *This summary is an abbreviated version of the research and does not contain the full content. For the full research, please visit our sponsor Dassault Systèmes BIOVIA (registration required). If you have difficulty obtaining a copy of the report, please contact us. [post_title] => 5 Ways to Digitally Transform the Lab [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => lab-integration [to_ping] => [pinged] => [post_modified] => 2024-03-27 10:50:15 [post_modified_gmt] => 2024-03-27 14:50:15 [post_content_filtered] => [post_parent] => 0 [guid] => https://tech-clarity.com/?p=20039 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [8] => WP_Post Object ( [ID] => 20027 [post_author] => 2574 [post_date] => 2024-03-26 10:00:09 [post_date_gmt] => 2024-03-26 14:00:09 [post_content] =>
- Design data 2D & 3D CAD, including advanced MBD support
- PLM, PDM, and other data sources
- Other standard / neutral file formats like STEP, DXF, QIF, XML, and more
- Documents and other non-technical file types

- Anark Collaborate: A mobile-first hosted platform (on-prem or SaaS) that offers collaboration in context, with real-time chat, markup capabilities, and traceability. Team members can share, access, and discuss technical data with markups, notes, pictures, videos and chat.
- Anark Workstation: A desktop solution for engineers and other authors to create recipe-driven technical data packages.
- Anark Publish: Automation engine that understands and synchronizes data with PDM, PLM, and other systems and makes it available for Anark Collaborate.

Table of Contents
- Executive Summary
- Product Development is Critical to Business Strategies
- The Time Wasters
- Implications of Time Wasters to the Business
- A Solution to Avoid Time Wasters
- Business Value from PLM
- Extending PLM Use Results in Greater Satisfaction
- How Companies Implement PLM
- Additional Values Due to the Cloud
- Conclusions
- Recommendations
- About the Research
- Acknowledgments
Executive Summary
Engineers Impact Business Success Engineering is critical to exceptional heavy equipment design. Likewise, engineers are crucial to ensure designs incorporate customer requirements, stay within budget, and meet delivery dates. Therefore, empowering engineers is key to the successful execution of business strategies. Too Many Time Wasters Unfortunately, engineers report spending too much time on non-value-added work with too many interruptions, taking them away from critical engineering work. Furthermore, 96% of surveyed equipment companies say this loss in engineering productivity comes at a significant business cost due to missed deadlines, higher costs, and less innovation. One approach to overcome productivity losses is to manage product data better and make it accessible to those who need it, when they need it. Reclaiming Wasted Time This report identifies substantial engineering time wasters in the heavy equipment industry by examining survey results of industrial equipment manufacturers. The analysis focuses on these results from the perspective of a heavy equipment company. This report explores how companies of all sizes reclaim lost time by examining the use and value of PLM (Product Lifecycle Management) solutions to centralize data across multiple domains, manage processes, and collaborate better. Incidentally, PLM users reported fewer changes due to outdated information and errors, significantly reducing non-value-added work and shortening development times. This report also examines how companies select and use PLM solutions, including cloud-based implementations.Implications of Time Wasters to the Business

Extending PLM Use Results in Greater Satisfaction

Conclusions
Reclaiming Lost Time Heavy equipment companies prioritize their future growth and sustained success on winning in the marketplace with better, differentiated equipment. To support this, they can significantly boost their product development capabilities by eliminating time wasters that consume engineers' valuable time. Equipment manufacturers find that PLM can empower their engineers to innovate by significantly reducing engineers' time on non-value-added tasks. As a result, they can enjoy a competitive advantage. In addition, technological advances, such as cloud-based offerings, can reduce implementation time, cost, and difficulty, making PLM more accessible. *This summary is an abbreviated version of the research and does not contain the full content. For the full research, please visit our sponsor Siemens (registration required). If you have difficulty obtaining a copy of the report, please contact us. [post_title] => Heavy Equipment: Reducing Engineering Time Wasters [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => heavy-equipment [to_ping] => [pinged] => [post_modified] => 2024-03-14 10:25:15 [post_modified_gmt] => 2024-03-14 14:25:15 [post_content_filtered] => [post_parent] => 0 [guid] => https://tech-clarity.com/?p=19977 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [11] => WP_Post Object ( [ID] => 19988 [post_author] => 2574 [post_date] => 2024-03-13 09:00:36 [post_date_gmt] => 2024-03-13 13:00:36 [post_content] =>

Table of Contents
- Executive Summary
- Product Development is Critical to Business Strategies
- The Time Wasters
- Implications of Time Wasters to the Business
- A Solution to Avoid Time Wasters
- Business Value from PLM
- Extending PLM Use Results in Greater Satisfaction
- How Companies Implement PLM
- Additional Values Due to the Cloud
- Conclusions
- Recommendations
- About the Research
- Acknowledgments
Executive Summary

The Time Wasters
What Slows Engineers Down? The graph identifies the top engineering time wasters aerospace and defense companies face. The findings highlight how much they waste on non-value-added work. Consequently, they need better ways to automate tedious tasks, especially those associated with compliance documentation, so they can focus more energy on adding value. Another top-ranking time waster, too many manual processes/ bottlenecks, emphasizes this further. Interruptions Similarly, constant interruptions to answer questions, share data, and provide updates also slow engineers down. These interruptions break an engineer's train of thought and distract them from their work. Yet, engineers still need convenient ways to easily exchange data with suppliers, OEMs, and engineers across domains to prevent working with outdated data. Limited Reuse Interconnected systems of mechanical components, electronics, and software are incredibly complex. If engineers can leverage compliant, proven, and tested subsystems and components, they will save time, reduce the risk of errors, and spend less effort on new certifications. However, the number of components across multiple engineering domains and suppliers makes it very difficult to find needed data, and searching for it wastes valuable time. To avoid these issues, engineers need suitable methods for finding what they need. Lack of Traceability Changes to complex, interconnected systems can require significant effort without easy methods for identifying the change's impacts. Traceability makes this possible. Traceability also makes compliance management significantly easier. It makes it possible to determine what's been verified and tested to meet regulatory and safety requirements. Then when tests fail, you can quickly identify what's impacted by the failure. Consequently, traceability can significantly reduce the manual burden of certification. Unfortunately, the manual document-driven processes common at aerospace and defense companies substantially limit traceability.
Conclusions
Reclaiming Lost Time
Aerospace and defense companies prioritize their future growth and sustained success on winning in the marketplace with better, differentiated offerings. To support this, they can significantly boost their product development capabilities by eliminating time wasters that consume engineers' valuable time.
Aerospace and defense manufacturers find that PLM can empower their engineers to innovate by significantly reducing engineers' time on non-value-added tasks. As a result, they can enjoy a competitive advantage. In addition, technological advances, such as cloud-based offerings, can reduce implementation time, cost, and difficulty, making PLM more accessible.
*This summary is an abbreviated version of the research and does not contain the full content. For the full research, please visit our sponsor Siemens (registration required).
If you have difficulty obtaining a copy of the report, please contact us.
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Table of Contents
- A Changing Life Sciences World
- Extreme Pressure on Production Operation
- The Flexibility Imperative
- Flexibility Challenges
- The Paperless Imperative
- Graphic: Paperless Benefits and Capabilities
- Challenges of Going Paperless
- MES or Manufacturing Operations Software
- MES Definition and Role
- How MES Addresses Flexibility Challenges
- How MES Enables Paperless
- Advanced MES Capabilities
- A Healthy BioPharma Future
The Need to be Flexible and Paperless

Extreme Pressure on Production Operations
Pressures Mount The pharmaceutical industry was once high-margin and relatively safe and consistent. However, more competition and new situations mean challenges from many angles. Four pressures are at the forefront: time, quality, compliance, and innovation. Time Time pressure is a multifaceted pressure—Time-to-market for new or smaller population therapies and time-to-deliver existing products to customers and patients who need them. Quality Patient safety and efficacy depend on end-to-end quality. This is not new, but the number of sites and companies involved often is. Compliance Regulators expect more from pharmaceutical manufacturers every year. Now, these expectations include digital approaches to speed the process and minimize chances for error. Innovation To succeed, companies are building a broad portfolio of products for multiple markets with specific regulations and needs. The innovation is often in related therapeutic areas to build strength in revenues and reputation. Beyond Tradeoffs Companies must seek no longer only tradeoffs between time, quality, compliance, and innovation. Pharmaceutical companies that pursue becoming flexible and paperless are on a path to enable all four simultaneously.“We have a program for digital transformation in manufacturing particularly, also in Quality and other areas. The key is implementation of eBR.” Nina Mikadze, Digital Transformation Leader, PHARMA INDUSTRY
How MES Addresses Flexibility Challenges
MES with eBR Design eBR design capabilities can ensure any need is pre-designed for operations. Having designs that support a variety of possibilities means that the MES workflow can handle a higher mix rapidly and confidently. This up-front, behind-the-scenes work streamlines activities for those in production. People can handle the increased mix of flexible manufacturing much more confidently and with higher assurance. Multi-product Design Space Regulators want more therapies to reach patients who need them, so they have created guidelines for validated processes to handle more than a single process or product in a process design space. Using MES, companies can seamlessly leverage the specs and recipes or bills of process for a wide variety of products. This risk-based approach and the new CSA guidance will help ensure that validated processes can be flexible. Auto-Document MES automatically documents everything that occurs. It can also error-proof processes for each specific product. So, no matter how many products are in play in a given shift, MES can ensure they are processed correctly and document the details of each unit’s processing, including CFR21 Part 11 compliant e-signatures. Assurance In pharma, implementing MES is a matter of setting it up for every product. This means pivoting to process correctly, document thoroughly, and ensure quality. As a result, you can be assured that human error is minimized. This also makes the process easy to audit. With MES, all this happens during the process; after-the-fact assurance efforts vanish. Accurate data is a given with MES.
A Healthy BioPharma Future
Imperatives to Change
Pharmaceutical companies of every stripe urgently need to modernize and move to paperless, flexible operations. Time, quality, compliance, and innovation pressures apply to pharmaceutical, biotech, cell and gene therapy, API, and other suppliers to the industry. Those who don’t yet have a commercial, modern MES to address them are likely to suffer in the face of competition that does.
Key Take-Aways
- In today’s world, all eight aspects of industrial competitiveness matter:7 agile, innovative, resilient, engaging, responsive, insightful, sustainable, and improving.
- MES is a foundation for flexible and paperless operations and quality.
- Ensure you get modern and pharma-experienced MES to provide eBR and beyond.
- Evaluate your business strategy and match your focus for production software to meet both short-term and long-term needs for flexibility.
- Educate everyone on the value of paper-free documentation and provide training and systems that make it natural.
- Ensure the MES has advanced capabilities and works with newer technologies that can deliver value. According to Deloitte research, most pharma companies have used the cloud, wearables, and AR/VR already.8
- Make the move to MES positive for the workers using it – by selecting the right software, educating them up front, and setting it up to support and empower them.
- Set a strategy to digitalize your company and ecosystem and keep at it.

Table of Contents
- Take a Systemic Approach
- 1) Develop Sustainability Requirements
- 2) Focus on Product Sustainability
- 3) Focus on Manufacturing Sustainability
- 4) Focus on Service and Operational Sustainability
- 5) Monitor, Track, and Report Sustainability Progress
- Conclusions / Call to Action
- Acknowledgments
It's Time to Operationalize Sustainability
Sustainability Dominates Business Strategies Sustainability is experiencing increased urgency in corporate strategies. Driven by regulation and customer demand, among other drivers, it is rapidly moving from a topic of discussion to a business imperative for manufacturers. Our 2022 survey on executive strategies saw the biggest inflection toward environmental, sustainability, and governance (ESG) action that we’ve seen. The percentage of companies that view environmental sustainability and corporate social responsibility as critical to long-term business success has grown by double digits.Take a Systemic Approach
Put Sustainability Strategy into Action Strategy without action doesn’t create results, however, and putting sustainability goals into action is a big challenge for manufacturers today. Manufacturers have difficulty approaching it because the problem is multi-faceted and they struggle to define their priorities. Should they focus on their own sustainability? Their suppliers’ ESG performance? The contents of their products? Or the impact their products have in use by customers? Then where should they start? Beyond defining goals, how will they support and measure the progress of their initiatives? Manufacturers need to address these questions in a systematic way and make hard tradeoffs to improve their sustainability – and their business. They need to take a systematic, data-driven approach to achieve their goals, leveraging and extending the data in the digital thread to operationalize sustainability. Focus Sustainability Efforts Sustainability is a complex topic. For example, greenhouse gas (GHG) emissions alone are typically broken down into three different “scopes” based on their source. And that’s only one aspect of sustainability.“CO2 is one thing, but not the only thing. We have a push for more circularity, how we get raw materials from the supply chain, and how to ensure the steel we get is sustainable.” – Technical Director, Fluid Transfer Systems Manufacturer.

- Their direct business (buildings, vehicles, etc.)
- The makeup / contents of their products including materials and the impact of their supply chain
- Their production, including energy, water, waste, consumables
- The impact of customers / users / operators using the product and how it affects their ESG goals
Jeff Stroh, Sr. Director Digital & Information Systems Management for McDermott International, explained the rationale for his business. “We are in a very carbon-intensive industry. We did a study of a liquid natural gas (LNG) facility on scopes 1,2, and 3. We found that the biggest impact we can have, even though we can do a lot different things, is in the first year our customer operates the plant.”That gives them a focus area to improve that will make a tangible difference. Take a Systems View First, manufacturers need to instill a company culture that rewards sustainability. Then, it can take a systems view to navigate the complexity, interrelationships, and tradeoffs required to make meaningful sustainability improvements. They must take into account all of the demands they face, both internal and external, and identify where they can couple doing the right thing with tangible business benefits like cost reduction. At that point, they can set requirements and goals for each. With that, they can take a holistic view to understand how potential actions will impact the targets and other implications they may have across the business so they can evaluate tradeoffs. Then, companies must monitor and track the plans across the business to fulfill the requirements and achieve their sustainability goals. This eBook shares five different ways manufacturers can improve ESG by taking a systems engineering approach.
Conclusions / Call to Action
Get Started Sustainability is being driven by customers and regulations and is quickly becoming a high priority in corporate agendas. And, it is just good business.According to Jeff Stroh of McDermott, “ESG is increasingly becoming a pre-requisite for bid eligibility, with more customers screening contractors such as McDermott for ESG criteria.”Manufacturers need to develop a culture that values sustainability across the enterprise. Then, they should take a holistic, systems approach, setting specific sustainability goals, breaking their strategic plans down into achievable systems requirements, and defining associated measurements and responsibilities. Support the Effort Driving sustainability improvements requires a systems-level approach. It requires manufacturers to move from a document-driven to a data-driven approach, leveraging robust digital threads and digital twins that incorporate data from a variety of sources. The data gathering, collaboration, and decision-making tools to drive new levels of sustainability – whether they focus on products, manufacturing, or operations – must be both comprehensive and agile. There is no “killer app” for sustainability, it requires an integrated ecosystem of collaborators, internal data, external databases, enterprise solutions, and tools throughout the product lifecycle. For example, solutions like LCA can be helpful, but they are often employed too late. Leverage PLM for Sustainability


- Are traditional algorithmic and simulation approaches to optimization still working with the current volatility and uncertainty?
- Have you used digital twins for your supply chain? How is that working?
- Are you optimizing at all levels: strategic, tactical, and operational? Are some more effective than others? Are there barriers?
- Are machine learning and related advanced analytics helping with optimization?
- Do you see a role for Generative AI or other new approaches?
- Beyond technologies, are there new processes, and mindsets needed for optimization and scenario planning?


Denodo helps companies create a single view of distributed data to drive analytics. As one would expect, the offering provides data integration, management, quality, and governance. But Denodo’s solution does not aggregate and replicate large volumes of data, instead creating a form of data mesh by sourcing and storing metadata while leaving data in place, but accessible. They then use the metadata to create a data catalog that allows self-service data discovery and data preparation on a logical abstraction of a variety of data stores. Although Denodo takes a “logical first” approach, leading with virtualization, they can also support ETL, ESBs, or APIs with over 200 adapters for complete data management and delivery.
Our research shows that manufacturers typically invest significant time and effort in creating and maintaining integrated data to drive decisions and support AI. In particular, they struggle to put IT and OT data in context. Denodo’s abstraction layer and services could play a significant role in simplifying this and deliver significant benefits.
[caption id="attachment_19829" align="aligncenter" width="824"]
The real value comes by putting the data into action. Denodo provides connectivity to data analysis tools like Tableau or PowerBI to turn that data into actionable insights. In this way, their data virtualization approach can help create intelligence from fragmented and proliferated data in real time without waiting for traditional extract, transformation, and load (ETL) processes.
We’ve seen some case studies and we’re impressed, but we also have more to learn. We believe that Denodo can offer significant value to support manufacturing and supply chain analytics and AI with their data fabric approach. Thank you, Dave Nixon, for making the connection, and Saptarshi Sengupta and Deborah Wiltshire for introducing us to Denodo’s capabilities. We look forward to continuing our learning and watching their progress in manufacturing industries.
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I caught up with an old friend who has an exciting new role as Executive Board Member and Co-Owner of PDTec, a company that I am excited to get to know better. The company offers a series of composable apps based on their data management platform, ice. NET. I love their tagline “innovation through integration” and their focus spanning data, process, and systems integration. Their solutions, based on a scalable component architecture, are designed to help engineers be more effective and efficient in product development, including:
- Simulation and systems engineering data management - SimData Manager
- PDM / PLM - CAD Portal
- Data exchange for tasks like supplier integration and collaboration - PDMconnect
In addition to these preconfigured standard offerings, PDTec can leverage their component-based platform to develop unique solutions on a consultative basis driven by their deep industry expertise.

PDTec is a company I look forward to learning more about. Thank you Michael Murgai for the overview.
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Artificial Intelligence
Not surprisingly, one of the biggest takeaways from AU2023 was related to the increased attention being placed on artificial intelligence (AI). AI was a central conference theme and it’s clear that Autodesk believes in its potential. Autodesk CEO Andrew Anagnost dedicated a portion of his keynote highlighting the ability for AI to change the way people work. Although a lot of the attention in the market today is about generative AI, thanks to the increased attention created by ChatGPT, Andrew also pointed out how AI can automate away non-value-added (NVA) work. A tangible example of automating repetitive, NVA tasks with AI is creating drawings and documentation with Fusion automated drawings. Autodesk shared other examples across the industries they serve.
Design & Manufacturing - PLM
We were also excited to get an update on the solutions for the manufacturing industries. Given that one of the biggest challenges with AI initiatives is having trusted, organized data we’ll start with data management. We were excited to see Autodesk integrate a “PLM Summit” into AU. The summit was a dedicated track for PLM customers to learn how to get business value from PLM. It was a well-organized, well-attended, collaborative event that primarily focused on Fusion 360 Manage and allowed users to openly share tips and techniques and what they’ve accomplished with the system. [caption id="attachment_19629" align="aligncenter" width="935"]

Design & Manufacturing - General
As the vision for Fusion shows, Autodesk design and manufacturing goes beyond PLM. AU gave us the opportunity to hear from EVP Design & Manufacturing Jeff Kinder and others about how they support the industry. Jeff shared a number of updates and customer stories, including how Rivian uses Fusion to develop more / faster prototypes, create real-time rendering, ensure design and manufacturability, and manufacture using CAM / CNC to machine prototype parts. Rivian spoke as well, explaining how Fusion enables them to work on a common data model to understand if a design is manufacturable, and if not change it in the design tab and move back to the manufacturing tab. They also shared how they leverage VR / AR to eliminate early physical models using VRED. This is a great example of how Fusion is intended to work across functions. In fact, Rivian shared how Autodesk can help a manufacturer with everything from AEC for the plant to line planning and factory layout, all in the same data model. As Jeff Hammoud, Rivian Chief Design Officer, shares, Fusion provides “seamless data sharing across the organization.” This helps them rethink not just their product, but their manufacturing processes. There is so much more to share, including a new partnership with Cadence and well-received enhancements to existing products like Vault with numerous user-driven enhancements and Inventor adding IFC in Inventor for industrialized construction and sheet metal tools. There isn’t room to share it all.Design & Manufacturing – Supporting The Factory
One last area I want to focus on is the factory. Autodesk is the “design and make” company. Their strategy goes beyond engineering to the plant. They’ve extended their factory planning and manufacturing portfolio by partnering with CloudNC for AI toolpaths and acquiring a factory simulation solution to extend their ability to help manufacturing engineers understand factory flow and bottlenecks. Beyond that, it will be very interesting to see what they do with Prodsmart and how they evolve to support plant operations. I asked Steve Hooper, VP Product Development, about future for manufacturing planning and execution. He mentioned that they already have capabilities for manufacturing engineers / process planners, from the plant / facility design, 1D planning, factory design, CAM, and CNC. He explained that he does see going deeper to support others who are left out of factory technology and need a digital thread solution that extends to lines, workcells, and workers. We’ll be watching this space. [caption id="attachment_19625" align="aligncenter" width="889"]
Architecture, Engineering, Design, and Construction (AEC)
We also heard from Amy Bunszel, EVP of AEC Design and Jim Lynch Senior VP, GM of Autodesk Construction Solutions. In a similar way to manufacturing, supporting AEC is all about the data. Autodesk continues to invest in BIM, with industry-leading Revit solution moving to Forma, their industry cloud for AEC. As Amy explains, “Forma is AI-powered design.” Autodesk shared some great examples of using AI in AEC to test different concepts, showing the impact of designs on sunlight, noise, and solar array positioning, and shared that these kinds of capabilities will eventually cover the entire BIM process. [caption id="attachment_19620" align="aligncenter" width="957"]
Autodesk Platform Services
Sitting behind the industry solutions for manufacturing, AEC, and media & entertainment is the Autodesk Platform. As announced at AU last year, The Forge platform is now Autodesk Platform Services (APS). APS is a significant investment in the future, shared across all industries. They’ve taken a data-centric approach with a granular data model, interoperable apps, and APIs on the cloud. Autodesk took this approach early and started from the ground up with the fundamentals. Autodesk shared some updates including continued investment in APIs and Autodesk Docs, offering cloud document management and a common data environment (CDE). Autodesk is extending what is already one of the most advanced platform strategies. Again, this is a space to watch as the Autodesk Platform continues to mature and offer comparable capabilities on a cloud platform.Summary
There is a lot that I’ve left out, but I hope this gives you an idea of what we took away from the event. Thank you to Jason Love, Christa Prokos, and the entire Autodesk University team for coordinating our AU2023 experience and putting together such great learning opportunities. [post_title] => Reflections on AI, PLM, and more from Autodesk University [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => autodesk-ai [to_ping] => [pinged] => [post_modified] => 2024-01-30 12:22:56 [post_modified_gmt] => 2024-01-30 17:22:56 [post_content_filtered] => [post_parent] => 0 [guid] => https://tech-clarity.com/?p=19614 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 20 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 20191 [post_author] => 2574 [post_date] => 2024-05-02 09:00:22 [post_date_gmt] => 2024-05-02 13:00:22 [post_content] =>
Table of Contents
- Executive Overview
- New Era in Manufacturing
- The Problem-Solving Story
- Five New-Era CI Needs
- New Era in Manufacturing
- Expected and Engaging
- Distributed and Elevated
- Diverse Yet Harmonized
- Learning-focused and Digital
- Enabling CI Sequels
- Recommendations
- Acknowledgments
- About the Author
Executive Overview
There’s a new Era in Manufacturing; it is time for a new era of continuous improvement (CI). This is a time of digital approaches delivering an array of new capabilities and insights that can move the business beyond unpleasant trade-offs. In this new era, CI gets enterprise-wide standardization and support and keeps the enthusiasm of local teams and employees. It delivers both local breakthroughs and views that support executives in understanding progress and prioritizing resources for the following CI projects in ways that make sense to everyone. Appropriate digitalization enables CI teams to get rapid and reliable access to all the data they need from a wide variety of sources. Beyond that, it supports them in gaining rich insights from the data with far less effort than ever before. Goals and results are translated into a shared, visceral unit of improvement that matters to shop floor operators, supervisors, managers, and executives: time. By feeding shared understanding, this digitally-supported CI will more likely generate enthusiasm and benefits even as the business shifts and changes.
The Problem-Solving Story
Path to Success
The Toyota Way points to a complete approach to solving problems – or making systemic improvements. The elements are:
- Developing a thorough understanding of the current situation and define the problem
- Complete a thorough root cause analysis
- Thoroughly consider alternative solutions while building consensus
- Plan-Do-Check-Act (PDCA)
- Plan: Develop an action plan
- Do: Implement solutions rapidly
- Check: Verify the result
- Act: Make necessary adjustments to solutions and action plan and determine future steps
- Reflect and learn from the process
Enabling CI Sequels
Each step of the CI story can benefit from having digital data available.
- Understanding: The complete set of correct data easily available and analyzed leads to a deeper understanding of the current situation and an accurate definition of the problem.
- RCA: Completing a thorough root cause analysis, such as tree diagramming, is faster and more assured when data is accessible, trusted, and complete.
- Modeling alternative solutions: When all parties trust and can see the data and its provenance, modeling to evaluate alternatives can be a clear and effective way to build consensus.
- Plan-Do-Check-Act (PDCA):
- Plan: Developing and recording the action plan in an IT system enables all to see and contribute equally.
- Do: Implementing solutions can come sooner when generating the plan is faster and the means to monitor progress is in place. The digital system can also help keep everyone in sync with rapid action.
- Check: Evaluating is a data-based exercise, so having a coherent system designed to record progress and unintended consequences in an unbiased and automatic way can contribute to effective and efficient CI.
- Act: Everyone can also participate fully and trust when they can see the basis for making necessary adjustments to solutions and the action plan
- Reflect: A consistent digital system can also facilitate learning from the process. People agree on the data and can use the system to record what they learned and what logic they used to direct future projects.
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